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Catalog NEPHROTOXICITY: Major side effect of anti-cancer drug: Drug-associated renal dysfunction ISBN-10 9783659384325, ISBN-13 978-3659384
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NEPHROTOXICITY: Major side effect of anti-cancer drug: Drug-associated renal dysfunction

Cisplatin (CDDP) is a major antineoplastic drug for the treatment of solid tumors such as metastatic bladder, testicular, and ovarian carcinomas. The drug can cause much toxicity, but the chief dose-limiting one is nephrotoxicity. Several, often interrelated mechanisms of actions have been hypothesized to induce the nephrotoxicity. These include apoptosis and inflammatory mechanism, production of tumor necrosis factor (TNF)-α by renal parenchymal...

By Dhairya Y. Joshi
Paperback: 64 pages
Publisher: LAP LAMBERT Academic Publishing (April 25, 2013)
Language: English
ISBN-10: 9783659384325
ISBN-13: 978-3659384325
ASIN: 3659384321
Product Dimensions: 5.9 x 0.2 x 8.7 inches
Format: PDF ePub TXT ebook

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Cisplatin (CDDP) is a major antineoplastic drug for the treatment of solid tumors such as metastatic bladder, testicular, and ovarian carcinomas. The drug can cause much toxicity, but the chief dose-limiting one is nephrotoxicity. Several, often interrelated mechanisms of actions have been hypothesized to induce the nephrotoxicity. These include apoptosis and inflammatory mechanism, production of tumor necrosis factor (TNF)-α by renal parenchymal...
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